Circulating microparticles are associated with plaque burden and cause eNOS uncoupling in patients with carotid atherosclerosis

Circulating microparticles are associated with plaque burden and cause eNOS uncoupling in patients with carotid atherosclerosis

Aims: The study aimed to evaluate the correlation of different microparticle (MP) phenotypes with plaque burden and their diagnostic value and preliminarily explore the role of MPs in atherosclerosis (AS).Methods: Carotid intima-media thickness (CIMT) and maximal plaque area in 23 patients with caro...

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Bibliographic Details
Main Authors: Xiaowan Han, Tong Li, Tieshan Wang, Baofu Wang, Yang Li, Lei Wang, Ziwen Lu, Aiming Wu, Lisong Liu, Guozhong Pan, Mingjing Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
carotid atherosclerosis
circulating microparticles
endothelial dysfunction
endothelial nitric oxide synthase uncoupling
leukocyte-derived microparticle
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.976644/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.976644/full

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