FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation

Abstract Background Fucosyltransferase 2(FUT2) and its induced α-1,2 fucosylation is associated with cancer metastasis. However, the role of FUT2 in colorectal cancer (CRC) metastasis remains unclear. Methods The expression levels and clinical analyses of FUT2 were assessed in CRC samples. Migration...

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Bibliographic Details
Main Authors: Lingnan He, Zijun Guo, Weijun Wang, Shuxin Tian, Rong Lin
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01060-0