Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects
Background: Immunogenicity refers to the inherent ability of a molecule to stimulate an immune response. Aggregates are one of the major risk factors for the undesired immunogenicity of therapeutic antibodies (Ab) and may ultimately result in immune-mediated adverse effects. For Ab delivered by inha...
Autors principals: | , , , , , , , , , , |
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Format: | Article |
Idioma: | English |
Publicat: |
MDPI AG
2022-03-01
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Col·lecció: | Pharmaceutics |
Matèries: | |
Accés en línia: | https://www.mdpi.com/1999-4923/14/3/671 |