Clozapine-Encapsulated Binary Mixed Micelles in Thermosensitive Sol–Gels for Intranasal Administration

Clozapine-Encapsulated Binary Mixed Micelles in Thermosensitive Sol–Gels for Intranasal Administration

(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach. This study aims to develop clozapine-encapsulated thermosensitive sol–gels for N2B delivery. (2) Methods: Poloxamer 40...

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Bibliographic Details
Main Authors: Madeleine S. A. Tan, Preeti Pandey, James R. Falconer, Dan J. Siskind, Alexandra Balmanno, Harendra S. Parekh
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Gels
Subjects:
antipsychotic
cardiomyopathy
clozapine
constipation
hydrogel
hypersalivation
Online Access:https://www.mdpi.com/2310-2861/8/1/38

Internet

https://www.mdpi.com/2310-2861/8/1/38

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