Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation
The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-13554-y |