Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation
The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.
Bibliographic Details
| Main Authors: |
Shunsuke Hasegawa,
Hotaka Fukushima,
Hiroshi Hosoda,
Tatsurou Serita,
Rie Ishikawa,
Tomohiro Rokukawa,
Ryouka Kawahara-Miki,
Yue Zhang,
Miho Ohta,
Shintaro Okada,
Toshiyuki Tanimizu,
Sheena A. Josselyn,
Paul W. Frankland,
Satoshi Kida |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-13554-y
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