Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype

Crosstalk between glomerular endothelial cells and glomerular epithelial cells (podocytes) is increasingly becoming apparent as a crucial mechanism to maintain the integrity of the glomerular filtration barrier. However, <i>in vitro</i> studies directly investigating the effect of this c...

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Bibliographic Details
Main Authors: Daan C. ‘t Hart, Dilemin Yildiz, Valentina Palacio-Castañeda, Lanhui Li, Burcu Gumuscu, Roland Brock, Wouter P. R. Verdurmen, Johan van der Vlag, Tom Nijenhuis
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biosensors
Subjects:
organ-on-a-chip
glomerulus
glomerulus-on-a-chip
co-culture
glomerular filtration barrier
crosstalk
Online Access:https://www.mdpi.com/2079-6374/13/3/339

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https://www.mdpi.com/2079-6374/13/3/339

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