CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds.

CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds.

In silico methods of phenotypic screening are necessary to reduce the time and cost of the experimental in vivo screening of anticancer agents through dozens of millions of natural and synthetic chemical compounds. We used the previously developed PASS (Prediction of Activity Spectra for Substances)...

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Main Authors: Alexey A Lagunin, Varvara I Dubovskaja, Anastasia V Rudik, Pavel V Pogodin, Dmitry S Druzhilovskiy, Tatyana A Gloriozova, Dmitry A Filimonov, Narahari G Sastry, Vladimir V Poroikov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5784992?pdf=render

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http://europepmc.org/articles/PMC5784992?pdf=render

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