LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines

LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines

Abstract Leukocyte-associated immunoglobulin-like receptor-1 (LAIR1), an immune receptor containing immunoreceptor tyrosine-based inhibiory motifs (ITIMs), has emerged as an attractive target for cancer therapy. However, the intrinsic function of LAIR1 in gliomas remains unclear. In this study, the...

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Bibliographic Details
Main Authors: Xiaoqian Wei, Shushan Pan, Zirui Wang, Jieru Chen, Li Lu, Qizhi Cao, Shuling Song, Huachang Zhang, Xiaohui Liu, Xianjun Qu, Xiukun Lin, Huanli Xu
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06199-9

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https://doi.org/10.1038/s41419-023-06199-9

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