Comprehensive characterization of enhancer RNA in hepatocellular carcinoma reveals three immune subtypes with implications for immunotherapy

Comprehensive characterization of enhancer RNA in hepatocellular carcinoma reveals three immune subtypes with implications for immunotherapy

Hepatocellular carcinoma (HCC) is highly heterogeneous. Molecular subtyping for guiding immunotherapy is warranted. Previous studies have indicated that enhancer RNAs (eRNAs) are involved in tumor heterogeneity and immune infiltration. However, the eRNA landscape and its correlation with immune infi...

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Bibliographic Details
Main Authors: Xiaoyun Bu, Shuang Liu, Dongsheng Wen, Anna Kan, Yujie Xu, Xuanjia Lin, Ming Shi
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
hepatocellular carcinoma
immune subtyping
enhancer RNA
immunotherapy response
heterogeneity
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000900

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http://www.sciencedirect.com/science/article/pii/S2372770522000900

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