BIOINFORMATICS STUDY OF 7,8-DIHYDROXYFLAVONE AS A NEUROPROTECTIVE AGENT IN ISCHEMIC STROKE VIA TRKB REGULATION AND GLUTAMINASE INHIBITION

BIOINFORMATICS STUDY OF 7,8-DIHYDROXYFLAVONE AS A NEUROPROTECTIVE AGENT IN ISCHEMIC STROKE VIA TRKB REGULATION AND GLUTAMINASE INHIBITION

Background: Stroke, particularly ischemic stroke, is one of the leading causes of death worldwide. Ischemic stroke causes a failure of oxidative phosphorylation and ATP synthesis, resulting in high levels of reactive oxygen species (ROS), neuroinflammatory responses, and apoptosis, all of which resu...

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Main Authors: Rislan Faiz Muhammad, Basya Adnani, Safira Dita Arviana, Aldita Husna Violita, Husnul Khotimah, Shahdevi Nandar Kurniawan, Mokhamad Fahmi Rizki Syaban, Yuyun Yueniwati Prabowowati Wadjib, Masruroh Rahayu
Format: Article
Language:English
Published: University of Brawijaya 2023-06-01
Series:Malang Neurology Journal
Subjects:
7,8-dihydroxyflavone
in silico
ischemic stroke
trkb
glutaminase
glutamate
Online Access:https://mnj.ub.ac.id/index.php/mnj/article/view/664

Internet

https://mnj.ub.ac.id/index.php/mnj/article/view/664

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