Intestinal permeability of agaro-oligosaccharides: Transport across Caco-2 cell monolayers and pharmacokinetics in rats

Intestinal permeability of agaro-oligosaccharides: Transport across Caco-2 cell monolayers and pharmacokinetics in rats

Agaro-oligosaccharides (AOSs), even-numbered oligosaccharides prepared from agar, are applied to various food, including supplements, drinks, and jellies because of their biological activities. This study aimed to evaluate the AOS permeation in the gastrointestinal tract in vivo and in vitro. Agarob...

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Bibliographic Details
Main Authors: Ikuya Shirai, Koji Karasawa, Yusuke Kodaira, Yu Iwasaki, Yasutaka Shigemura, Hidefumi Makabe, Shigeru Katayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Nutrition
Subjects:
agaro-oligosaccharide
Caco-2
intestinal permeability
paracellular pathway
agarobiose
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.996607/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.996607/full

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