Condemned or Not to Die? Gene Polymorphisms Associated With Cell Death in Pemphigus Foliaceus

Condemned or Not to Die? Gene Polymorphisms Associated With Cell Death in Pemphigus Foliaceus

Pemphigus foliaceus (PF) is an autoimmune blistering skin disease that occurs sporadically across the globe and is endemic in Brazil. Keratinocyte adhesion loss (acantholysis) is associated with high levels of anti-desmoglein 1 IgG autoantibodies, but the role of cell death is poorly understood in P...

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Bibliographic Details
Main Authors: Valéria Bumiller-Bini, Gabriel Adelman Cipolla, Mariana Basso Spadoni, Danillo Gardenal Augusto, Maria Luiza Petzl-Erler, Marcia Holsbach Beltrame, Angelica Beate Winter Boldt
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
pemphigus
cell death
skin disease
autoimmune disease
apoptosis
pyroptosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02416/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02416/full

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