The Molecular Chaperone Artemin Efficiently Blocks Fibrillization of TAU Protein In Vitro
Objective: Aggregation of the TAU proteins in the form of neurofibrillary tangles (NFTs) in the brain is a common risk factor in tauopathies including Alzheimer’s disease (AD). Several strategies have been implemented to target NFTs, among which chaperones, which facilitate the proper folding of p...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2017-11-01
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Series: | Cell Journal |
Subjects: | |
Online Access: | http://celljournal.org/journal/article/16341/download |