The Molecular Chaperone Artemin Efficiently Blocks Fibrillization of TAU Protein In Vitro

Objective: Aggregation of the TAU proteins in the form of neurofibrillary tangles (NFTs) in the brain is a common risk factor in tauopathies including Alzheimer’s disease (AD). Several strategies have been implemented to target NFTs, among which chaperones, which facilitate the proper folding of p...

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Bibliographic Details
Main Authors: Zahra Khosravi, Mohammad Ali Nasiri Khalili, Sharif Moradi, Reza Hassan Sajedi, Mehdi Zeinoddini
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2017-11-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/journal/article/16341/download