CCAST: a model-based gating strategy to isolate homogeneous subpopulations in a heterogeneous population of single cells.

A model-based gating strategy is developed for sorting cells and analyzing populations of single cells. The strategy, named CCAST, for Clustering, Classification and Sorting Tree, identifies a gating strategy for isolating homogeneous subpopulations from a heterogeneous population of single cells us...

Full description

Bibliographic Details
Main Authors: Benedict Anchang, Mary T Do, Xi Zhao, Sylvia K Plevritis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4117418?pdf=render