Downregulation of pro-surfactant protein B contributes to the recurrence of early-stage non-small cell lung cancer by activating PGK1-mediated Akt signaling

Downregulation of pro-surfactant protein B contributes to the recurrence of early-stage non-small cell lung cancer by activating PGK1-mediated Akt signaling

Abstract Recurrence is one of the main causes of treatment failure in early-stage non-small cell lung cancer (NSCLC). However, there are no predictors of the recurrence of early-stage NSCLC, and the molecular mechanism of its recurrence is not clear. In this study, we used clinical sample analysis t...

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Bibliographic Details
Main Authors: Hao Luo, Qing Li, Ren-Tao Wang, Liang Zhang, Wei Zhang, Meng-Sheng Deng, Yuan-Yuan Luo, Xintong Ji, Yongheng Wen, Xuan-Rui Zhou, Bo Xu, Dong Wang, Bin Hu, Hua Jin, Cheng-Xiong Xu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Experimental Hematology & Oncology
Subjects:
Recurrence
Early-stage NSCLC
Pro-SFTPB
PGK1
Akt pathway
Online Access:https://doi.org/10.1186/s40164-023-00455-6

Internet

https://doi.org/10.1186/s40164-023-00455-6

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