Synthesis and Biological Evaluation of Carvacrol-Based Derivatives as Dual Inhibitors of <i>H. pylori</i> Strains and AGS Cell Proliferation

Synthesis and Biological Evaluation of Carvacrol-Based Derivatives as Dual Inhibitors of <i>H. pylori</i> Strains and AGS Cell Proliferation

This study reports on the synthesis, structural assessment, microbiological screening against several strains of <i>H. pylori</i> and antiproliferative activity against human gastric adenocarcinoma (AGS) cells of a large series of carvacrol-based compounds. Structural analyses consisted...

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Bibliographic Details
Main Authors: Francesca Sisto, Simone Carradori, Paolo Guglielmi, Carmen Beatrice Traversi, Mattia Spano, Anatoly P. Sobolev, Daniela Secci, Maria Carmela Di Marcantonio, Entela Haloci, Rossella Grande, Gabriella Mincione
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
carvacrol
<i>Helicobacter pylori</i>
AGS cells
semi-synthesis
drug resistance
dual agent
Online Access:https://www.mdpi.com/1424-8247/13/11/405

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https://www.mdpi.com/1424-8247/13/11/405

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