Syndecan-1 as a severity biomarker for patients with trauma

Syndecan-1 as a severity biomarker for patients with trauma

Tissue injury and hemorrhage induced by trauma lead to degradation of the endothelial glycocalyx, causing syndecan-1 (SDC-1) to be shed into the blood. In this study, we investigated whether serum SDC-1 is useful for evaluating trauma severity in patients. A single-center, retrospective, observation...

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Bibliographic Details
Main Authors: Keiko Suzuki, Hideshi Okada, Kazuyuki Sumi, Hiroyuki Tomita, Ryo Kobayashi, Takuma Ishihara, Yosuke Mizuno, Fuminori Yamaji, Ryo Kamidani, Tomotaka Miura, Ryu Yasuda, Yuichiro Kitagawa, Tetsuya Fukuta, Kodai Suzuki, Takahito Miyake, Norihide Kanda, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Nobuyuki Tetsuka, Shinji Ogura, Akio Suzuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
trauma
syndecan-1
injury severity score
glycocalyx
probability of survival
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.985955/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.985955/full

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