KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3

KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3

Abstract Background N6-methyladenosine (m6A) modification, the most abundant internal methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the largest known component in the m6A methyltransferase complex, KIAA1429 plays a vital role in m6A methylation. However, i...

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Bibliographic Details
Main Authors: Tian Lan, Hui Li, Delin Zhang, Lin Xu, Hailing Liu, Xiangyong Hao, Xiaokai Yan, Haotian Liao, Xiangzheng Chen, Kunlin Xie, Jiaxin Li, Mingheng Liao, Jiwei Huang, Kefei Yuan, Yong Zeng, Hong Wu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Cancer
Subjects:
Hepatocellular carcinoma
N6-methyladenosine
KIAA1429
GATA3
GATA3-AS
Online Access:https://doi.org/10.1186/s12943-019-1106-z

Internet

https://doi.org/10.1186/s12943-019-1106-z

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