The role, mechanism, and application of RNA methyltransferase METTL14 in gastrointestinal cancer

The role, mechanism, and application of RNA methyltransferase METTL14 in gastrointestinal cancer

Abstract Gastrointestinal cancer is the most common human malignancy characterized by high lethality and poor prognosis. Emerging evidences indicate that N6-methyladenosine (m6A), the most abundant post-transcriptional modification in eukaryotes, exerts important roles in regulating mRNA metabolism...

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Bibliographic Details
Main Authors: Bin Shi, Wei-Wei Liu, Ke Yang, Guan-Min Jiang, Hao Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Molecular Cancer
Subjects:
Gastrointestinal cancer
RNA modification
m6A
METTL14
Online Access:https://doi.org/10.1186/s12943-022-01634-5

Internet

https://doi.org/10.1186/s12943-022-01634-5

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