PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer

PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer

<i>Background and Objectives</i>: PNU-74654, a Wnt/β-catenin pathway inhibitor, has an antiproliferative effect on many cancer types; however, its therapeutic role in pancreatic cancer (PC) has not yet been demonstrated. Here, the effects of PNU-74654 on proliferation and cell cycle phas...

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Bibliographic Details
Main Authors: Tai-Long Chien, Yao-Cheng Wu, Hsiang-Lin Lee, Wen-Wei Sung, Chia-Ying Yu, Ya-Chuan Chang, Chun-Che Lin, Chi-Chih Wang, Ming-Chang Tsai
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Medicina
Subjects:
pancreatic adenocarcinoma
β-catenin
WNT
cell cycle arrest
migration
Online Access:https://www.mdpi.com/1648-9144/59/9/1531

Internet

https://www.mdpi.com/1648-9144/59/9/1531

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