Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

Abstract Background KDM5 family proteins are multi-domain regulators of transcription that when dysregulated contribute to cancer and intellectual disability. KDM5 proteins can regulate transcription through their histone demethylase activity in addition to demethylase-independent gene regulatory fu...

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Bibliographic Details
Main Authors: Matanel Yheskel, Simone Sidoli, Julie Secombe
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Epigenetics & Chromatin
Subjects:
KDM5
Histone demethylase
TurboID
Proximity labeling
Mass spectrometry
Chromatin modifiers
Online Access:https://doi.org/10.1186/s13072-023-00481-y

Internet

https://doi.org/10.1186/s13072-023-00481-y

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