Update on the pathological roles of prostaglandin E2 in neurodegeneration in amyotrophic lateral sclerosis

Update on the pathological roles of prostaglandin E2 in neurodegeneration in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. The pathogenesis of ALS remains largely unknown; however, inflammation of the spinal cord is a focus of ALS research and an important path...

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Bibliographic Details
Main Authors: Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi, Yuri Aono, Tadashi Saigusa, Yasuhiro Kosuge
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Translational Neurodegeneration
Subjects:
Prostaglandin E2
Amyotrophic lateral sclerosis
Motor neuron death
E-prostanoid receptor
Microsomal prostaglandin E synthetase-1
Online Access:https://doi.org/10.1186/s40035-023-00366-w

Internet

https://doi.org/10.1186/s40035-023-00366-w

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