Clinical Significance of IGFBP-3 Methylation in Patients with Early Stage Gastric Cancer

Clinical Significance of IGFBP-3 Methylation in Patients with Early Stage Gastric Cancer

BACKGROUND: IGFBP-3 is a multifunctional protein that inhibits growth and induces apoptosis of cancer cells. Hypermethylation of the promoter represses expression of the IGFBP-3 gene. We undertook this study to assess the impact of IGFBP-3 methylation on survival of early stage gastric cancer patien...

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Main Authors: Seung Tae Kim, Hye-Lim Jang, Jeeyun Lee, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Min Gew Choi, Jae Moon Bae, Tae Sung Sohn, Jae Hyung Noh, Sung Kim, Kyoung-Mee Kim, Won Ki Kang, Joon Oh Park
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523315000510

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http://www.sciencedirect.com/science/article/pii/S1936523315000510

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