Possible Mechanisms by which Stefin B could Regulate Proteostasis and Oxidative Stress

Human stefin B is a protease inhibitor from the family of cystatins. It was reported that it forms oligomers in cells. We have shown that it has a role in cell’s response to misfolded proteins. We also have shown that its oligomers bind amyloid-beta (Aβ). Here, we discuss ways, ho...

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Bibliographic Details
Main Author: Eva Žerovnik
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/1/70