Possible Mechanisms by which Stefin B could Regulate Proteostasis and Oxidative Stress
Human stefin B is a protease inhibitor from the family of cystatins. It was reported that it forms oligomers in cells. We have shown that it has a role in cell’s response to misfolded proteins. We also have shown that its oligomers bind amyloid-beta (Aβ). Here, we discuss ways, ho...
Main Author: | Eva Žerovnik |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
|
Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/8/1/70 |
Similar Items
-
Human stefin B: from its structure, folding, and aggregation to its function in health and disease
by: Eva Žerovnik, et al.
Published: (2022-10-01) -
Amyloid Formation of Stefin B Protein Studied by Infrared Spectroscopy
by: Urban Novak, et al.
Published: (2023-03-01) -
Stefin B Inhibits NLRP3 Inflammasome Activation via AMPK/mTOR Signalling
by: Mojca Trstenjak-Prebanda, et al.
Published: (2023-11-01) -
The Toxicity and Polymorphism of β-Amyloid Oligomers
by: Ya-ru Huang, et al.
Published: (2020-06-01) -
Synergy of the Inhibitory Action of Polyphenols Plus Vitamin C on Amyloid Fibril Formation: Case Study of Human Stefin B
by: Alma Jahić Mujkić, et al.
Published: (2021-09-01)