Detection of Alu Exonization Events in Human Frontal Cortex From RNA-Seq Data

Detection of Alu Exonization Events in Human Frontal Cortex From RNA-Seq Data

Alu exonization events functionally diversify the transcriptome, creating alternative mRNA isoforms and accounting for an estimated 5% of the alternatively spliced (skipped) exons in the human genome. We developed computational methods, implemented into a software called Alubaster, for detecting inc...

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Bibliographic Details
Main Authors: Liliana Florea, Lindsay Payer, Corina Antonescu, Guangyu Yang, Kathleen Burns
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alu exonization
alternative splicing
RNA sequencing
computational prediction
frontal cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.727537/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.727537/full

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