Cerebrolysin alleviates early brain injury after traumatic brain injury by inhibiting neuroinflammation and apoptosis via TLR signaling pathway

Cerebrolysin alleviates early brain injury after traumatic brain injury by inhibiting neuroinflammation and apoptosis via TLR signaling pathway

ABSTRACT Purpose: Traumatic brain injury (TBI) is a major cause of death and disability. Cerebrolysin (CBL) has been reported to be anti-inflammatory by reducing reactive oxygen species (ROS) production. However, the neuroprotection of CBL in TBI and the potential mechanism are unclear. We aimed to...

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Bibliographic Details
Main Authors: Weihong Lu, Zhonghua Zhu, Dongliang Shi, Xiaoyu Li, Jingzhi Luo, Xingzhi Liao
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022-09-01
Series:Acta Cirúrgica Brasileira
Subjects:
Brain Injuries, Traumatic
Neuroinflammatory Diseases
Apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000600203&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000600203&lng=en&tlng=en

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