Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling

Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling

BackgroundEarlier, we reported that the simultaneous exposure of pulmonary arterial smooth muscle cells to HIV proteins and cocaine results in the attenuation of antiproliferative bone morphogenetic protein receptor‐2 (BMPR2) protein expression without any decrease in its mRNA levels. Therefore, in...

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Bibliographic Details
Main Authors: Mahendran Chinnappan, Aradhana Mohan, Stuti Agarwal, Pranjali Dalvi, Navneet K. Dhillon
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cocaine
drug abuse
human immunodeficiency virus
human immunodeficiency virus tat
intravenous drug use
microRNA
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008472

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.008472

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