Macrophages produce PGE2 to promote hepatic stellate cell autophagy and liver fibrosis

The pathogenesis of liver fibrosis in nonalcoholic fatty liver disease (NAFLD) remains unclear and the effective treatments have not been explored yet. The activation of hepatic stellate cells (HSCs) is the most critical factor in the progression of liver fibrosis. Macroautophagy/autophagy has recen...

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Bibliographic Details
Main Authors: Liuluan Zhu, Yanxi Zhou, Rui Li, Shuwei Deng
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Autophagy Reports
Subjects:
Online Access:http://dx.doi.org/10.1080/27694127.2022.2119513