Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade

Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade

Abstract Background Interactions between tumor and microenvironment determine individual response to immunotherapy. Triple negative breast cancer (TNBC) and hepatocellular carcinoma (HCC) have exhibited suboptimal responses to immune checkpoint inhibitors (ICIs). Aspartate β-hydroxylase (ASPH), an o...

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Bibliographic Details
Main Authors: Xuewei Bai, Yanmei Zhou, Yuki Yokota, Yoshihiro Matsumoto, Bo Zhai, Nader Maarouf, Hikaru Hayashi, Rolf Carlson, Songhua Zhang, Aryanna Sousa, Bei Sun, Hossein Ghanbari, Xiaoqun Dong, Jack R. Wands
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Aspartate β-hydroxylase (ASPH)
Immune checkpoint inhibitor
Lambda phage vaccine
Triple negative breast cancer
Hepatocellular carcinoma
Metastasis
Online Access:https://doi.org/10.1186/s13046-022-02307-3

Internet

https://doi.org/10.1186/s13046-022-02307-3

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