Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck

Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck

Cytokines are mediators of inflammation that could lead to fibrosis. The aim was to monitor cytokine levels in saliva and serum after locally fractionated radiotherapy of the head and neck in mice and investigate associations with salivary gland fibrosis and hyposalivation. C57BL/6 mice were randomi...

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Bibliographic Details
Main Authors: Olga Zlygosteva, Inga Solgård Juvkam, Hans Christian D. Aass, Hilde K. Galtung, Tine M. Søland, Eirik Malinen, Nina F. J. Edin
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
cytokines
X-rays
fractionated radiotherapy
normal tissue response
head and neck
salivary glands
Online Access:https://www.mdpi.com/1422-0067/24/20/15218

Internet

https://www.mdpi.com/1422-0067/24/20/15218

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