Single-cell RNA-Seq reveals transcriptional heterogeneity and immune subtypes associated with disease activity in human myasthenia gravis

Abstract Myasthenia gravis (MG) is a rare autoimmune disease. Although the impact of immune cell disorder in MG has been extensively studied, little is known about the transcriptomes of individual cells. Here, we assessed the transcriptional profiles of 39,243 cells by single-cell sequencing and ide...

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Bibliographic Details
Main Authors: Wanlin Jin, Qi Yang, Yuyao Peng, Chengkai Yan, Yi Li, Zhaohui Luo, Bo Xiao, Liqun Xu, Huan Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00314-w