HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data.

The liver performs many essential metabolic functions, which can be studied using computational models of hepatocytes. Here we present HepatoDyn, a highly detailed dynamic model of hepatocyte metabolism. HepatoDyn includes a large metabolic network, highly detailed kinetic laws, and is capable of dy...

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Bibliographic Details
Main Authors: Carles Foguet, Silvia Marin, Vitaly A Selivanov, Eric Fanchon, Wai-Nang Paul Lee, Joan J Guinovart, Pedro de Atauri, Marta Cascante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004899