Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal Effects
Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly mediated by two exotoxins: toxin A (TcdA) and toxin B (TcdB). These toxins primarily disrupt the cytoskeletal struct...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-05-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/8/5/134 |