Motivational and Valence‐Related Modulation of Sleep/Wake Behavior are Mediated by Midbrain Dopamine and Uncoupled from the Homeostatic and Circadian Processes

Abstract Motivation and its hedonic valence are powerful modulators of sleep/wake behavior, yet its underlying mechanism is still poorly understood. Given the well‐established role of midbrain dopamine (mDA) neurons in encoding motivation and emotional valence, here, neuronal mechanisms mediating sl...

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Bibliographic Details
Main Authors: Karim Fifel, Amina El Farissi, Yoan Cherasse, Masashi Yanagisawa
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202200640