PEP-sNASP Peptide Alleviates LPS-Induced Acute Lung Injury Through the TLR4/TRAF6 Axis

PEP-sNASP Peptide Alleviates LPS-Induced Acute Lung Injury Through the TLR4/TRAF6 Axis

Acute lung injury (ALI) is a severe inflammatory lung disease associated with macrophages. Somatic nuclear autoantigenic sperm protein (sNASP) is a negative regulator of Toll-like receptor (TLR) signaling that targets tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) in macrophages, w...

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Bibliographic Details
Main Authors: Yu-Chih Wu, Sung-Po Hsu, Meng-Chun Hu, Yu-Ting Lan, Edward T. H. Yeh, Feng-Ming Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Medicine
Subjects:
TLR4
TRAF6
inflammation
acute lung injury
NASP
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.832713/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.832713/full

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