Macrophage alternative activation confers protection against lipotoxicity-induced cell death

Macrophage alternative activation confers protection against lipotoxicity-induced cell death

Objective: Alternative activation (M2) of adipose tissue resident macrophage (ATM) inhibits obesity-induced metabolic inflammation. The underlying mechanisms remain unclear. Recent studies have shown that dysregulated lipid homeostasis caused by increased lipolysis in white adipose tissue (WAT) in t...

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Bibliographic Details
Main Authors: Lingling Dai, Prerna Bhargava, Kristopher J. Stanya, Ryan K. Alexander, Yae-Huei Liou, David Jacobi, Nelson H. Knudsen, Alexander Hyde, Matthew R. Gangl, Sihao Liu, Chih-Hao Lee
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Molecular Metabolism
Subjects:
Obesity
Adipose tissue macrophage
Alternative activation
Lipotoxicity
Meta-inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817305239

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http://www.sciencedirect.com/science/article/pii/S2212877817305239

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