Detection of a novel mutations in Exon 11 of BRCA1 gene in the patients with hereditary breast cancer

Introduction: Breast cancer is the most common malignancy in women worldwide. BRCA1 is a tumor suppressor gene that is involved in DNA-damage repair. One of the significant risk factors of breast cancer is the family history. BRCA1 gene consists of 24 exons that encode a protein with 1863 amino acid...

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Bibliographic Details
Main Authors: seyed mohsen miresmaeili, seyed mehdi kalantar
Format: Article
Language:fas
Published: Shahid Sadoughi University of Medical Sciences 2019-01-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Subjects:
Online Access:http://jssu.ssu.ac.ir/browse.php?a_code=A-10-25-3&slc_lang=en&sid=1