Photochemical Restoration of Light Sensitivity in the Degenerated Canine Retina

Photochemical Restoration of Light Sensitivity in the Degenerated Canine Retina

Photopharmacological compounds such as azobenzene-based photoswitches have been shown to control the conductivity of ionic channels in a light-dependent manner and are considered a potential strategy to restore vision in patients with end-stage photoreceptor degeneration. Here, we report the effects...

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Bibliographic Details
Main Authors: Sergei Nikonov, Natalia Dolgova, Raghavi Sudharsan, Ivan Tochitsky, Simone Iwabe, Jose-Manuel Guzman, Russell N. Van Gelder, Richard H. Kramer, Gustavo D. Aguirre, William A. Beltran
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
photopharmacology
photoswitch
DENAQ
vision restoration
retinal degeneration
canine
Online Access:https://www.mdpi.com/1999-4923/14/12/2711

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https://www.mdpi.com/1999-4923/14/12/2711

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