Role of TRPC1 channels in pressure-mediated activation of airway remodeling

Abstract Background Bronchoconstriction and cough, a characteristic of the asthmatic response, leads to development of compressive stresses in the airway wall. We hypothesized that progressively pathological high mechanical stress could act on mechanosensitive cation channels, such as transient rece...

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Bibliographic Details
Main Authors: Na Li, Ye He, Gang Yang, Qian Yu, Minchao Li
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-019-1050-x