Targeted delivery of 5-fluorouracil, miR-532-3p, and si-KRAS to the colorectal tumor using layer-by-layer liposomes

Targeted delivery of 5-fluorouracil, miR-532-3p, and si-KRAS to the colorectal tumor using layer-by-layer liposomes

Co-delivery of siRNA or miRNA with chemotherapeutic drugs into tumor sites is an attractive synergetic strategy for treating colorectal cancer (CRC) due to their complementary mechanisms. In the current work, a liposome nanoparticle (Huang et al., Cancer Metastasis Rev., 2018, 37, 173–187) coated by...

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Bibliographic Details
Main Authors: Maryamsadat Shahidi, Omid Abazari, Parisa Dayati, Bibi Fatemeh Haghiralsadat, Fatemeh Oroojalian, Davood Tofighi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
colorectal cancer
liposome
MiR-532-3p
si-KRAS
5-fluorouracil
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1013541/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1013541/full

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