Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes
Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding sequences of certain genes in response to physiological demands. We previously identified C-to-U RNA editing (C136U, R46X) which inactivates a small fraction of succinate dehydrogenase (SDH; mitochondria...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-09-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/152.pdf |