Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes

Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding sequences of certain genes in response to physiological demands. We previously identified C-to-U RNA editing (C136U, R46X) which inactivates a small fraction of succinate dehydrogenase (SDH; mitochondria...

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Bibliographic Details
Main Authors: Bora E. Baysal, Kitty De Jong, Biao Liu, Jianmin Wang, Santosh K. Patnaik, Paul K. Wallace, Robert T. Taggart
Format: Article
Language:English
Published: PeerJ Inc. 2013-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/152.pdf