Glucose Increase DAGLα Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose

Glucose Increase DAGLα Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose

The endocannabinoid system (ECS) is composed of a group of Gi-coupled protein receptors and enzymes, producing and degrading the endocannabinoids, 2-arachidonoylglycerol (2-AG) and N-arachidonoyl-ethanolamine (AEA). Endocannabinoid-mediated signaling modulates brain functions, such as pain, mood, me...

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Bibliographic Details
Main Authors: Alejandra Palma-Chavez, Macarena Konar-Nié, Patricio Órdenes, Felipe Maurelia, Roberto Elizondo-Vega, Karina Oyarce, Sergio López, Joaquin Rojas, Ximena Steinberg, María A. García-Robles, Fernando J. Sepúlveda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Endocrinology
Subjects:
feeding behavior
endocannabinoid system
hypothalamus
DAGLα
Tanycytes
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00647/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00647/full

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