A new approach for the induction of vitiligo in mice

Tyrosinase has been recognized as a major autoantign in human vitiligo. Here we have shown that experimental autoimmune vitiligo can be induced by intradermal injection of mushroom tyrosinase emulsified in complete Freund’s adjuvant in C57BL/6 mice. The onse of vitiligo was characterized by hair hyp...

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Bibliographic Details
Main Authors: Zehtab T, Rafieii Tehranie S, Yazdanparast R
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2000-08-01
Series:Acta Medica Iranica
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1258.pdf&manuscript_id=1258