Effects of mineralocorticoid receptor overexpression on anxiety and memory after early life stress in female mice

Effects of mineralocorticoid receptor overexpression on anxiety and memory after early life stress in female mice

Early-life stress is a risk factor for the development of psychopathology, particularly in women. Human studies have shown that certain haplotypes of NR3C2, encoding the mineralocorticoid receptor (MR), that result in gain of function, may protect against the consequences of stress exposure, includi...

Full description

Bibliographic Details
Main Authors: Sofia eKanatsou, Judith P Ter Horst, Anjanette P Harris, Jonathan R Seckl, Harmen J Krugers, Marian eJoels
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Anxiety
Fear
spatial memory
Mineralocorticoid Receptors
Early life adversity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00374/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00374/full

Similar Items