β-Carotene accelerates the resolution of atherosclerosis in mice

β-Carotene oxygenase 1 (BCO1) catalyzes the cleavage of β-carotene to form vitamin A. Besides its role in vision, vitamin A regulates the expression of genes involved in lipid metabolism and immune cell differentiation. BCO1 activity is associated with the reduction of plasma cholesterol in humans a...

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Bibliographic Details
Main Authors: Ivan Pinos, Johana Coronel, Asma'a Albakri, Amparo Blanco, Patrick McQueen, Donald Molina, JaeYoung Sim, Edward A Fisher, Jaume Amengual
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/87430