Unraveling the impact of upfront chemotherapy and proton beam therapy on treatment outcome and follow-up in central nervous system germ cell tumors: a single center experience

Unraveling the impact of upfront chemotherapy and proton beam therapy on treatment outcome and follow-up in central nervous system germ cell tumors: a single center experience

BackgroundGerm cell tumors (GCT) account for a minority of central nervous system (CNS) malignancies, highly prevalent in adolescents and young adults. Despite their aggressive biological behavior, prognosis is excellent in most cases with risk stratified treatment, consisting in a combination of ch...

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Bibliographic Details
Main Authors: Giada Del Baldo, Sabina Vennarini, Maristella Toniutti, Rachid Abbas, Stefano Lorentini, Eleonora Piccirilli, Antonella Cacchione, Giacomina Megaro, Valentina Di Ruscio, Maria Antonietta De Ioris, Andrea De Salvo, Giulia Albino, Sabrina Rossi, Giovanna Stefania Colafati, Andrea Carai, Angela Mastronuzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
CNS germ cell tumors
chemotherapy
protontherapy
outcome
side effects
pediatric brain tumors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1259403/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1259403/full

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