Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex

Abstract Background Stem cell niche maintains stem cell population identity and is essential for the homeostasis of self-renewal and differentiation in Drosophila testes. However, the mechanisms of CySC lineage signals-mediated soma–germline communications in response to external stimuli are unclear...

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Bibliographic Details
Main Authors: Zhiran Li, Yunhao Wu, Yangbo Fu, Xia Chen, Xi Zhao, Xiaolong Wu, Yajuan Lu, Hui He, Cong Shen, Bo Zheng, Jun Yu, Fei Sun
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-03025-5