Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

Summary: Type I interferons (IFNs) are essential innate immune proteins that maintain tissue homeostasis through tonic expression and can be upregulated to drive antiviral resistance and inflammation upon stimulation. However, the mechanisms that inhibit aberrant IFN upregulation in homeostasis and...

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Bibliographic Details
Main Authors: Yaqiu Wang, Rajendra Karki, Raghvendra Mall, Bhesh Raj Sharma, Ravi C. Kalathur, SangJoon Lee, Balabhaskararao Kancharana, Matthew So, Katie L. Combs, Thirumala-Devi Kanneganti
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472201275X

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http://www.sciencedirect.com/science/article/pii/S221112472201275X

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